ABSTRACT
Propofol, a new intravenous anesthetic agent,is now used for brief operation and day case surgery for its characteristics on recovery and controllability. We evaluated fourteen and fifteen patients undergoing laryngeal microsurgery with N2O-O2-propofol and N2O-O2 enflurane anesthesia respectively. In propofol group, induction dose of 1.5-2.0 mg/kg according to age was followed by continuous infusion of 10mg/kg/h with infusion pump. In enflurane group thiopenthal 3-5mg /kg and N2O-O2-enflurane were administrated for induction and maintenance of anesthesia. We checked systolic blood pressure, diastolic blood pressure and heart rate. There were no significant differnce between propofol and enflurane group in systolic and diastolic blood pressure. But hesrt rate of propofol group was significantly lower than enflurane group. Propofol group showed significantly higher incidence of pain during injection. We checked recovery time from anesthesia. Propofol group showed significantly shorter recovery time than enflurane group. Postoperative emesis and vomiting were occurred 1 patient in each group. According to arterial blood gas analysis, ventilatory function in time of eye opening recovered to normal ranges in propofol group, but not in enflurane group. We conclude that propofol is a safe and effective anesthetic agent for laryngeal microsurgery.